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11
Dec

No “gay gene” says top scientists

From i09.com

Homosexuality ranks low in twin studies that attempt to quantify what behaviors are most caused by genetics. Some researchers have put forth the theory that male homosexuality tends to be genetic and female homosexuality is external and psychological factors.

This study, by top experts, suggests homosexuality is caused by “epi-marks” that control how genes are expressed. The primary reason is external environmental factors that occur before and shortly after birth.

From io9.com…

Writing in The Quarterly Review of Biology, researchers William Rice, a professor at the University of California, Santa Barbara, and Urban Friberg, a professor at Uppsala University in Sweden, believe that homosexuality can be explained by the presence of epi-marks — temporary switches that control how our genes are expressed during gestation and after we’re born.

Specifically, the researchers discovered sex-specific epi-marks which, unlike most genetic switches, get passed down from father to daughter or mother to son. Most epi-marks don’t normally pass between generations and are essentially “erased.” Rice and Friberg say this explains why homosexuality appears to run in families, yet has no real genetic underpinning.

Epigenetic mechanisms can be seen as an added layer of information that clings to our DNA. Epi-marks regulate the expression of genes according to the strength of external cues. Genes are basically the instruction book, while epi-marks direct how those instructions get carried out. For example, they can determine when, where, and how much of a gene gets expressed.

Moreover, epi-marks are usually produced from scratch with each generation — but new evidence is showing that they can sometimes carryover from parent to child. It’s this phenomenon that gives the impression of having shared genes with relatives.